Cancer treatment with chimeric antigen receptor (CAR)-T cells has actually attained remarkable remissions in particular hematologic malignancies, and extending the method to other kinds of cancer is an essential objective of immunotherapy research study. Strong growths have actually shown especially tough since of immunosuppressive systems in the growth microenvironment. Composing in ScienceDanino and associates describe a brand-new method for releasing CAR-T cells versus strong growths: utilize crafted germs to coat the interior of the growth with an artificial antigen and after that treat with CAR-T cells particular for the artificial antigen.
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Aschheim, K. A bacterial help for CAR-T cells.
Nat Biotechnol 411521 (2023 ). https://doi.org/10.1038/s41587-023-02042-w
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DOI: https://doi.org/10.1038/s41587-023-02042-w
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