19659001 News & & Views Released: 19459010 13 November 2023 Imaging Nature Biotechnology ( 19459020 2023 19459021 Mention this post Topics Neural connection in brain tissue is imaged by identifying the extracellular area. 19659008 Given that the early days of neuroanatomy, scientists had an option in between 2 opposed labeling techniques to image nerve cells and their circuits: label all or label couple of. In a research study in 19459028 Nature Biotechnology 19659009 1 , Michalska et al. advance a 3rd method, attaining a detailed view of the nerve system– to the level of synapses– by identifying the extracellular area in repaired tissue. This makes a brand-new opportunity of thick restorations of nerve cells in the brain offered to numerous laboratories that utilize an ever growing set of improved and super-resolution microscopy strategies. 19659011 This is a sneak peek of membership material, gain access to through your organization 19659012 Gain access to choices 19659013 Gain access to Nature and 54 other Nature Portfolio journals 19659014 Get Nature+, our best-value online-access membership 24,99 EUR 19459037/ 30 days cancel at any time Register for this journal Get 12 print problems and online gain access to 19659019 206,07 EUR each year 19659020 just 17,17 EUR per problem Lease or purchase this post 19659022 Rates differ by post type 19659023 from 19459021 $1.95 19659024 to $39.95 Rates might go through regional taxes which are determined throughout checkout 19659026 Extra gain access to alternatives: Visit 19659028 Learn more about institutional memberships Read our FAQs 19659030 Contact client assistance Fig. 1: Concept and workflow of CATS. 19659032 Referrals Michalska, J. M. et al. Nat. Biotechnol. 19659034 https://doi.org/10.1038/s41587-023-01911-8 (2023). Post PubMed Google Scholar 19459012 19659036 Swanson, L. W. & & Lichtman, J. W. Annu. Rev. Neurosci. 19659037 39 , 197– 216 (2016 ). 19659038 Short article 19459012 CAS PubMed Google Scholar 19459012 19659039 Feng, G. et al. Nerve cell 28 , 41– 51(2000). Post 19459079 CAS PubMed 19459081 Google Scholar Livet, J. et al. Nature 19659043 450 , 56– 62(2007). 19659044 Short article. CAS PubMed 19459012 19459087 Google Scholar 19459012 Wickersham, I. R., Finke, S., Conzelmann, K. K. & Callaway, E. M. Nat. Approaches 4 , 47– 49 (2007). Post 19459012 CAS 19459012 19459092 PubMed 19459012 & 19459093 Google Scholar 19459012 19659048 Tønnesen, J., Inavalli, V. V. G. K. & Nägerl, U. V. Cell 172 , 1108– 1121. e15(2018). Short article 19459012 PubMed 19459012 Google Scholar Kitamura, K., Judkewitz, B., Kano, M., Denk, W. & Häusser, M. Nat. Techniques 19659052 5 , 61– 67 (2008). 19659053 Post 19459012 CAS PubMed 19459104 Google Scholar 19459012 19659054 Grassi, D. et al. Cell Rep. 42 , 112478(2023 ). Post 19459012 CAS 19459109 PubMed 19459110 PubMed Central 19459111 Google Scholar Pettus, E. H., Christman, C. W., Giebel, M. L. & Povlishock, J. T. 19459028 J. Neurotrauma 19659058 11 , 507– 522(1994). Post 19459012 CAS 19459012 PubMed Google Scholar 19459012 19659060 Williams, P. R. et al. 19459028 Nat. Commun. 5 19459052, 5683(2014). Short article CAS PubMed 19459012 Google Scholar Download referrals 19659064 Author details. Authors and Affiliations 19659066 Institute of Neuronal Cell Biology, Technical University of Munich (TUM), Munich, Germany 19659067 Shahrzad Askari & Thomas Misgeld 19659068 German Center for Neurodegenerative Diseases(DZNE), Munich, Germany 19659069 Thomas Misgeld Munich Cluster for Systems Neurology(SyNergy), Munich, Germany Thomas Misgeld Corresponding author 19659073 Correspondence to Thomas Misgeld 19659074 Principles statements 19659075 Contending interests 19659076 The authors state no contending interests. Rights and approvals About this post Look for updates. Confirm currency and credibility by means of CrossMark 19659080 Mention this short article 19659081 Askari, S., Misgeld, T. Brain imaging turned within out. Nat Biotechnol 19459019 (2023 ). https://doi.org/10.1038/s41587-023-02036-8 Download citation 19659083 Released : 13 November 2023 DOI : 19659087 https://doi.org/10.1038/s41587-023-02036-8 19659088 Associated material 19659089 Find out more
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